Biological Effects of Low Level Exposures BIOMEDICAL IMPLICATIONS OF HORMESIS – PART 2 TABLE OF CONTENTS
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چکیده
Aging is characterized by stochastic accumulation of molecular damage, progressive failure of maintenance and repair, and consequent onset of age-related diseases. Applying hormesis in aging research and therapy is based on the principle of stimulation of maintenance and repair pathways by repeated exposure to mild stress. Studies on the beneficial biological effects of repeated mild heat shock on human cells in culture, and other studies on the anti-aging and life prolonging effects of proxidants, hypergravity, irradiation, and ethanol on cells and organisms suggest that hormesis as an anti-aging and gerontomodulatory approach has a promising future. Its clinical applications include prevention and treatment of diabetes, cataract, osteoporosis, dementia and some cancers.
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